LAUSR

A 57-year-old woman with a medical background of tobacco use and chronic obstructive pulmonary disease was admitted to a clinic in Buenos Aires on April 24, 2020, with a 2-week history of diarrhea, abdominal pain, headache and retro-orbital pain, aching joints, dyspnea, subfebrile, pruritic rash, and unspecific thoracic pain. Upon admission, her vital signs were normal. A physical examination revealed a nonblanching, generalized rash with scattered petechiae predominantly on the extremities, upper trunk, and abdomen ( Fig. 1 ). Chest radiography and thoracic computed tomography showed no signs of pneumonia. There were no electrocardiographic changes, and cardiac biomarkers were negative; therefore, coronary syndrome was discarded. Laboratory examinations, including acute phase reactants, were all normal. A human immunodeficiency virus test was negative, and a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test from a nasopharyngeal swab test tested positive. A skin biopsy showed epidermal atrophy and marked superficial angiectasia, dermis with intense edema, and no associated inflammatory changes ( Fig. 2 ).