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Improvement of Primary Vulvar Langerhans Cell Histiocytosis with Lenalidomide

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Dear Editors, A 68-year-old woman presented to dermatology in August 2016 with a decades-long history of worsening recurrent, small, painful vulvar ulcers ( Fig. 1 A). The initial differential diagnosis… Click to show full abstract

Dear Editors, A 68-year-old woman presented to dermatology in August 2016 with a decades-long history of worsening recurrent, small, painful vulvar ulcers ( Fig. 1 A). The initial differential diagnosis was herpes simplex virus versus recurrent genital aphthae. The patient later developed rare crusted papules in the axilla ( Fig. 1 B), lower abdomen, and external auditory canals. Two initial vulvar biopsies showed nonspecific inflammatory changes. Topical and oral antibiotics, topical and oral corticosteroids, and antivirals were not

Keywords: primary vulvar; vulvar langerhans; vulvar; dermatology; improvement primary; langerhans cell

Journal Title: International Journal of Women's Dermatology
Year Published: 2021

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