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The regulatory mechanisms governing T cell exhaustion remain incompletely understood. Man et al. (2017) and Wu et al. (2017) report that the T cell receptor responsive transcription factor Irf4 promotes T cell exhaustion in chronic… Click to show full abstract
The regulatory mechanisms governing T cell exhaustion remain incompletely understood. Man et al. (2017) and Wu et al. (2017) report that the T cell receptor responsive transcription factor Irf4 promotes T cell exhaustion in chronic viral infection but dampens exhaustion in response to tissue allografts.
Keywords:
feeling exhausted;
exhausted tuning;
energizes dysfunctional;
irf4 energizes;
irf4;
tuning irf4
Journal Title: Immunity
Year Published: 2017
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Journal Title: Immunity
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!