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A Tuft Act to Follow: Leukotrienes Take the Stage in Anti-worm Immunity.

Tuft cells are specialized taste-chemosensory cells that detect the presence of intestinal parasites and orchestrate type 2 immunity. In this issue of Immunity, McGinty et al. discover that parasitic worms, but… Click to show full abstract

Tuft cells are specialized taste-chemosensory cells that detect the presence of intestinal parasites and orchestrate type 2 immunity. In this issue of Immunity, McGinty et al. discover that parasitic worms, but not commensal protists, stimulate tuft cells to release cysteinyl leukotrienes to amplify anti-helminth immunity in the small intestine.

Keywords: immunity; act follow; tuft; tuft act; immunity tuft; follow leukotrienes

Journal Title: Immunity
Year Published: 2020

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