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Summary Zhou et al. (Nature) and Hoffmann et al. (Cell) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain… Click to show full abstract
Summary Zhou et al. (Nature) and Hoffmann et al. (Cell) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain proinflammatory cytokine release via the associated angiotestin II pathway and a possible therapeutic target via the IL-6-STAT3 axis.
Keywords:
receptor;
cytokine release;
covid new;
new virus
Journal Title: Immunity
Year Published: 2020
Link to full text (if available)
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Journal Title: Immunity
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!