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Going viral: HBV-specific CD8+ tissue-resident memory T cells propagate anti-tumor immunity.

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The nature of the epitopes recognized by tumor-infiltrating T cells is not clearly defined. In this issue of Immunity, Cheng et al. demonstrate that tissue-resident memory CD8+ T cells specific for hepatitis B… Click to show full abstract

The nature of the epitopes recognized by tumor-infiltrating T cells is not clearly defined. In this issue of Immunity, Cheng et al. demonstrate that tissue-resident memory CD8+ T cells specific for hepatitis B virus-derived antigens exhibit potent anti-tumor properties and correlate with relapse-free survival in patients with resected hepatocellular carcinoma.

Keywords: immunity; tissue resident; anti tumor; resident memory; tumor

Journal Title: Immunity
Year Published: 2021

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