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Retinol is shuttled to myeloid cells for conversion to retinoic acid, but the receptor facilitating uptake of SAA:retinol complexes on myeloid cells is unknown. In a recent issue of Science,… Click to show full abstract
Retinol is shuttled to myeloid cells for conversion to retinoic acid, but the receptor facilitating uptake of SAA:retinol complexes on myeloid cells is unknown. In a recent issue of Science, Bang et al. (2021) use genetic and biochemical approaches to reveal this critical receptor to be LRP1 and show that this axis is essential for intestinal innate and adaptive immune responses.
Keywords:
keeps gut;
gut saafe;
slrp1 retinol;
retinol keeps;
retinol
Journal Title: Immunity
Year Published: 2021
Link to full text (if available)
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Journal Title: Immunity
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!