LAUSR

Abstract Senga Sengana is a common strawberry (Fragaria × ananassa Duch.) cultivar growing in southern Poland. From leaves of this popular horticultural plant six triterpenoids were obtained including one glycoside nigaichigoside F1. All compounds were isolated by repeated silica gel column chromatography and preparative HPLC on Reverse phase RP-18. Their structures were evaluated by modern HR-MS and NMR techniques. This is the first report concerning triterpenoids constituents in Senga Sengana cultivar leaves and the only one that describes isolation of these compounds from the strawberry leaves. From all compounds nigaichigoside F1 is the dominant constituent. Compound T1 (3β, 19α, 23α-trihydroxy-2-oxoolean-12-en-28-oic acid) is a new triterpenoid, not previously described in nature. As triterpenoids are responsible for many biological effects the strawberry leaf extracts enriched in triterpenoid constituents may also be involved in antifungal, antitumor, antidiabetic and antinociceptive activities. The latter two activities could be especially linked to the presence of euscaphic acid and nigaichigoside F1, respectively. Overall, this study suggests that strawberry leaves are a promising waste and a valuable source of bioactive compounds for the food and pharmaceutical industry.