Photo from wikipedia
Two studies show that adding NOTCH ligands to Flt3L cultures increases the yield of cDC1s from mouse and human progenitors. Moreover, these NOTCH-DCs more closely resemble in vivo DCs transcriptionally… Click to show full abstract
Two studies show that adding NOTCH ligands to Flt3L cultures increases the yield of cDC1s from mouse and human progenitors. Moreover, these NOTCH-DCs more closely resemble in vivo DCs transcriptionally and functionally. This will be extremely valuable for studying DCs in vitro and for further developing autologous DC-based antitumor vaccinations.
Keywords:
dcs;
production dendritic;
vitro production;
dendritic cells;
notching vitro
Journal Title: Trends in immunology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Trends in immunology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!