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In a recent study, Harrison et al. (Science 2019;363;eaat6280) report that RORγt-expressing skin commensal-specific T cells rapidly respond to tissue wounding by producing type 2 T helper cell (Th2) cytokines… Click to show full abstract
In a recent study, Harrison et al. (Science 2019;363;eaat6280) report that RORγt-expressing skin commensal-specific T cells rapidly respond to tissue wounding by producing type 2 T helper cell (Th2) cytokines in mice. The cells constitutively coexpress GATA-3 and type 2 cytokine mRNAs that are translated after injury. These T cells act as sentinels, linking T cell receptor (TCR) recognition of commensals, tissue damage, and wound repair.
Keywords:
producing cells;
cells support;
support repair;
repair;
skin producing
Journal Title: Trends in immunology
Year Published: 2019
Link to full text (if available)
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Journal Title: Trends in immunology
Year Published: 2019
Link to full text (if available)
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recommendations!