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Sensory Nerves Regulate Transcriptional Dynamics of Lymph Node Cells.

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The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that… Click to show full abstract

The nervous system plays important roles in homeostasis and inflammatory responses in tissues. However, the regulation of lymph nodes (LN) by nerves remains largely unknown. Huang et al. demonstrate that LNs are innervated by unique peptidergic nociceptors that signal to various endothelial, stromal, and immune cell types in LNs.

Keywords: transcriptional dynamics; dynamics lymph; sensory nerves; nerves regulate; regulate transcriptional; lymph node

Journal Title: Trends in immunology
Year Published: 2021

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