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The majority of patients presenting with vitiligo have a clinical sign of activity

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REFERENCES 1. Xing L, Dai Z, Jabbari A, et al. Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. Nat Med. 2014;20:1043-1049. 2. Liu LY,… Click to show full abstract

REFERENCES 1. Xing L, Dai Z, Jabbari A, et al. Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. Nat Med. 2014;20:1043-1049. 2. Liu LY, Craiglow B, Dai F, King BA. Tofacitinib for the treatment of severe alopecia areata and variants: results in 90 patients. J Am Acad Dermatol. 2017;76:22-28. 3. Schafer P. Apremilast mechanism of action and application to psoriasis and psoriatic arthritis. Biochem Pharmacol. 2012;83: 1583-1590. 4. Suarez-FarinasM, Ungar B, Noda S, et al. Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing. J Allergy Clin Immunol. 2015;136:1277-1287. 5. Keren A, Shemer A, Ullmann Y, Paus R, Gilhar A. The PDE4 inhibitor, apremilast, suppresses experimentally induced alopecia areata in human skin in vivo. J Dermatol Sci. 2015;77:74-76.

Keywords: majority patients; alopecia areata; presenting vitiligo; clinical sign; patients presenting; vitiligo clinical

Journal Title: Journal of the American Academy of Dermatology
Year Published: 2017

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