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Dipeptidyl Peptidase-4 Inhibition Prevents Vascular Calcification by Potentiating the Insulin-Like Growth Factor-1 Signaling Pathway

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Cardiovascular calcification is a growing burden and a leading contributor to acute cardiovascular events, but no therapeutics are currently available. Recently, Choi et al. [(1)][1] put forward dipeptidyl peptidase (DPP)-4 as… Click to show full abstract

Cardiovascular calcification is a growing burden and a leading contributor to acute cardiovascular events, but no therapeutics are currently available. Recently, Choi et al. [(1)][1] put forward dipeptidyl peptidase (DPP)-4 as a new pharmacological target to prevent aortic valve calcification. DPP-

Keywords: peptidase inhibition; inhibition prevents; calcification; prevents vascular; dipeptidyl peptidase

Journal Title: JACC: Basic to Translational Science
Year Published: 2019

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