Myocardial infarction (MI)-induced cardiac remodeling includes chamber dilatation, contractile dysfunction, and fibrosis. Of these, fibrosis is the least understood. After MI, activated cardiac fibroblasts deposit extracellular matrix, leading to pathological… Click to show full abstract
Myocardial infarction (MI)-induced cardiac remodeling includes chamber dilatation, contractile dysfunction, and fibrosis. Of these, fibrosis is the least understood. After MI, activated cardiac fibroblasts deposit extracellular matrix, leading to pathological myocardial fibrosis. Current therapies
               
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