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GW29-e1603 The effect of activin A-follistatin system imbalance on myocardial fibrosis of heart failure and the regulation of ghrelin

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Ghrelin, a novel growth hormone–releasing peptide, potentially improves cardiac function, but the mechanisms remain unclear. Activin A (Act A) is a member of the transforming growth factor beta (TGF-β) superfamily,… Click to show full abstract

Ghrelin, a novel growth hormone–releasing peptide, potentially improves cardiac function, but the mechanisms remain unclear. Activin A (Act A) is a member of the transforming growth factor beta (TGF-β) superfamily, which is closely associated with tissue fibrosis. Follistatin (FS), a key

Keywords: fibrosis; follistatin; effect activin; gw29 e1603; e1603 effect; ghrelin

Journal Title: Journal of the American College of Cardiology
Year Published: 2018

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