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GW29-e1697 Activation of Farnesoid X Receptor enhances the survival of engrafted adipose-derived mesenchymal stem cells in mouse post-MI heart

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The poor survival of engrafted stem cells in the ischemic environment limits their therapeutic efficacy for myocardial infarction (MI) treatment. Previously, we demonstrated that GW4064, an farnesoid X receptor (FXR)… Click to show full abstract

The poor survival of engrafted stem cells in the ischemic environment limits their therapeutic efficacy for myocardial infarction (MI) treatment. Previously, we demonstrated that GW4064, an farnesoid X receptor (FXR) agonist, ameliorated post-MI cardiac dysfunction and remodeling. The current study

Keywords: survival engrafted; stem cells; farnesoid receptor

Journal Title: Journal of the American College of Cardiology
Year Published: 2018

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