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Patterns of use, clinical efficacy, safety and tolerability of ketamine and esketamine in treatment-resistant depression: towards registry-based surveillance systems.

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More data on the long-term effects of racemic ketamine and esketamine in TDR patients is needed. The implementation of centralized registries of their use for treatment of depression could be… Click to show full abstract

More data on the long-term effects of racemic ketamine and esketamine in TDR patients is needed. The implementation of centralized registries of their use for treatment of depression could be a tool of major importance for assessing their efficacy and safety in real-world clinical practice. This paper seeks to outline the rise and rationale behind these registry-based surveillance systems.

Keywords: efficacy safety; surveillance systems; based surveillance; ketamine esketamine; registry based

Journal Title: Journal of affective disorders
Year Published: 2021

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