LAUSR

Abstract This current work deals with the study of the magnetic and biomedical characterization of La0.7Sr0.3Mn1-xBxO3 (B=Mo, Ti) nanoparticles for hyperthermia applications. Our nanoparticles were prepared through an aqueous combustion process (Glycine Nitrate Process, GNP), and are characterized with a mean crystallite size about 18 nm. The incorporation of Ti4+ and Mo6+ in Mn-site induced a structural transition from rhombohedral structure with R-3 C space group for La0.7Sr0.3MnO3 compound to orthorhombic one with Pnma space group for La0.7Sr0.3Mn0.95Mo0.05O3 and La0.7Sr0.3Mn0.95Ti0.05O3 compounds. The morphological properties indicated a variation in grain size ranging from 82 to 90 nm with doping extra element in manganese site. All samples exhibit a classical behavior from ferromagnetic (FM) to paramagnetic (PM) state as the temperature increases. A decrease in Curie temperature (TC) has been remarked from 84 °C to 70 °C and 82 °C for La0.7Sr0.3MnO3, La0.7Sr0.3Mn0.95Ti0.05O3, La0.7Sr0.3Mn0.95Mo0.05O3 respectively. According to the Arrott plots, the slopes of the curves of all the samples are positive, which is a signature of second order transition. The magnetic heating characteristics in AC field were measured in alternating magnetic fields of 23.89 mT at a fixed frequency of 518.7 kHz. The intrinsic loss power (ILP) has been calculated from SAR values. The different nanoparticles with a high ILP may be useful for the in situ hyperthermia treatment of cancer cells.