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Antibody Responses to Third-Dose mRNA Vaccines in Nursing Home and Assisted Living Residents

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A third-dose COVID-19 vaccination was recommended in US long-term care settings on September 24, 2021,1 though only half of eligible nursing home residents have received a third dose as of… Click to show full abstract

A third-dose COVID-19 vaccination was recommended in US long-term care settings on September 24, 2021,1 though only half of eligible nursing home residents have received a third dose as of December 5, 2021.2 On August 17, 2021, the province of Ontario, Canada, was relatively early to recommend a third-dose mRNA vaccination for residents in nursing home and assisted living settings in response to waning protection.3 Early real-world vaccine effectiveness data suggest substantially greater protection from Omicron (B.1.1.529; hereafter Omicron) infection for persons who have received a third-dose mRNA vaccine, compared with a 2-dose vaccination series.4 It is unclear if residents in long-term care settings mount a robust response to a third mRNA vaccination that may confer protection.

Keywords: nursing home; home assisted; dose mrna; assisted living; third dose

Journal Title: Journal of the American Medical Directors Association
Year Published: 2022

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