LAUSR

Cataracts are the most crucial cause of blindness among all ophthalmic diseases. Convenient and cost-effective early cataract screening is urgently needed to reduce the risks of visual loss. To date, many studies have investigated automatic cataract classification based on fundus images. However, existing methods mainly rely on global image information while ignoring various local and subtle features. Notably, these local features are highly helpful for the identification of cataracts with different severities. To avoid this disadvantage, we introduce a deep learning technique to learn multilevel feature representations of the fundus image simultaneously. Specifically, a global-local attention network (GLA-Net) is proposed to handle the cataract classification task, which consists of two levels of subnets: the global-level attention subnet pays attention to the global structure information of the fundus image, while the local-level attention subnet focuses on the local discriminative features of the specific regions. These two types of subnets extract retinal features at different attention levels, which are then combined for final cataract classification. Our GLA-Net achieves the best performance in all metrics (90.65% detection accuracy, 83.47% grading accuracy, and 81.11% classification accuracy of grades 1 and 2). The experimental results on a real clinical dataset show that the combination of global-level and local-level attention models is effective for cataract screening and provides significant potential for other medical tasks.