Highlights • The SOX9 expression increased in tumor tissues and peripheral blood of malignant and benign bone tumors.• The protein level of SOX9 is enhanced in malignant bone tumor tissues.•… Click to show full abstract
Highlights • The SOX9 expression increased in tumor tissues and peripheral blood of malignant and benign bone tumors.• The protein level of SOX9 is enhanced in malignant bone tumor tissues.• SOX9 over-expression correlated with tumor severity, grade, invasion feature, poor response to therapy, and recurrence.
               
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