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Highlights • FOXD3-AS1 downregulation inhibits cell migration, invasion and EMT in osteosarcoma.• Overexpression of miR-296-5p hinders the malignant behaviors of osteosarcoma cells.• FOXD3-AS1 sponges miR-296-5p to elevate ZCCHC3 to facilitate… Click to show full abstract
Highlights • FOXD3-AS1 downregulation inhibits cell migration, invasion and EMT in osteosarcoma.• Overexpression of miR-296-5p hinders the malignant behaviors of osteosarcoma cells.• FOXD3-AS1 sponges miR-296-5p to elevate ZCCHC3 to facilitate malignancy in osteosarcoma.• ELF1 activates FOXD3-AS1 to mediate tumor development in osteosarcoma.
Keywords:
emt osteosarcoma;
invasion emt;
mir 296;
osteosarcoma cells;
foxd3 as1;
migration invasion
Journal Title: Journal of Bone Oncology
Year Published: 2021
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Journal Title: Journal of Bone Oncology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!