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Hsa_circ_0010220 regulates miR-198/Syntaxin 6 axis to promote osteosarcoma progression

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Highlights • hsa_circ_0010220 expression is increased in osteosarcoma.• hsa_circ_0010220 knockdown represses cell proliferation, migration and invasion.• hsa_circ_0010220 regulates Syntaxin 6 via miR-198.• hsa_circ_0010220 silence decreases xenograft tumor growth. Click to show full abstract

Highlights • hsa_circ_0010220 expression is increased in osteosarcoma.• hsa_circ_0010220 knockdown represses cell proliferation, migration and invasion.• hsa_circ_0010220 regulates Syntaxin 6 via miR-198.• hsa_circ_0010220 silence decreases xenograft tumor growth.

Keywords: mir 198; hsa circ; circ 0010220; 0010220 regulates

Journal Title: Journal of Bone Oncology
Year Published: 2021

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