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Two-year results of a randomised trial comparing 4- versus 12-weekly bone-targeted agent use in patients with bone metastases from breast or castration-resistant prostate cancer

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Highlights • Optimal dosing interval of bone-targeting agents (BTAs) has not been fully defined.• Study of 4 vs 12-weekly BTAs in breast or prostate cancer pts with bone metastases.• Study… Click to show full abstract

Highlights • Optimal dosing interval of bone-targeting agents (BTAs) has not been fully defined.• Study of 4 vs 12-weekly BTAs in breast or prostate cancer pts with bone metastases.• Study arms showed no significant differences SSE rates, time to SSEs or toxicity.• There were however significant differences in cost-effectiveness results.• On study SSE (12-weekly arm) associated with slight increase in subsequent SSEs.

Keywords: bone metastases; two year; prostate cancer; bone; year results

Journal Title: Journal of Bone Oncology
Year Published: 2021

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