Highlights • Optimal dosing interval of bone-targeting agents (BTAs) has not been fully defined.• Study of 4 vs 12-weekly BTAs in breast or prostate cancer pts with bone metastases.• Study… Click to show full abstract
Highlights • Optimal dosing interval of bone-targeting agents (BTAs) has not been fully defined.• Study of 4 vs 12-weekly BTAs in breast or prostate cancer pts with bone metastases.• Study arms showed no significant differences SSE rates, time to SSEs or toxicity.• There were however significant differences in cost-effectiveness results.• On study SSE (12-weekly arm) associated with slight increase in subsequent SSEs.
               
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