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Herein we present an efficient carbonylative protocol for the introduction of an alkyl-acyl group into heteroarenes from cyclobutanone oximes. In the presence of Fe(OTf) 2 catalyst, proceeds via intermolecular alkyl-acylation… Click to show full abstract
Herein we present an efficient carbonylative protocol for the introduction of an alkyl-acyl group into heteroarenes from cyclobutanone oximes. In the presence of Fe(OTf) 2 catalyst, proceeds via intermolecular alkyl-acylation of different heteroarenes. A broad range of alkyl heteroaryl ketones are synthesized with excellent functional group tolerance with good chemoselectivity. © 2019 Elsevier Inc.
Keywords:
iron catalyzed;
catalyzed carbonylative;
carbonylative alkyl;
alkyl acylation;
acylation
Journal Title: Journal of Catalysis
Year Published: 2019
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Journal Title: Journal of Catalysis
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!