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Cyproterone Acetate-Induced Acute Liver Failure: A Case Report and Review of the Literature.

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Cyproterone acetate (CPA), a hydroxyprogesterone derivative, is used to treat advanced prostate cancer and infrequently in women for acne, breast cancer and hirsutism. Transient mild elevation in levels of liver enzymes… Click to show full abstract

Cyproterone acetate (CPA), a hydroxyprogesterone derivative, is used to treat advanced prostate cancer and infrequently in women for acne, breast cancer and hirsutism. Transient mild elevation in levels of liver enzymes is reported in 10-30% of patients, and acute liver failure (ALF) is uncommon. Here, we discuss the first case of CPA-induced ALF from India and the available literature.

Keywords: liver failure; acute liver; cyproterone acetate

Journal Title: Journal of clinical and experimental hepatology
Year Published: 2021

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