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Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy.

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Exogenous human herpes virus 6 (HHV-6) reinfection has never been reported in patients receiving tumor-infiltrating T lymphocytes therapy. We report an unusual case of HHV-6 infection following infusion of HHV-6… Click to show full abstract

Exogenous human herpes virus 6 (HHV-6) reinfection has never been reported in patients receiving tumor-infiltrating T lymphocytes therapy. We report an unusual case of HHV-6 infection following infusion of HHV-6 infected autologous T lymphocytes. HHV-6 infection could interfere with the tumor antigen immune recognition and the efficacy of immunotherapy.

Keywords: exogenous human; herpesvirus reinfection; human herpesvirus; tumor infiltrating; tumor

Journal Title: Cytotherapy
Year Published: 2018

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