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BMZ: basement membrane zone BP: bullous pemphigoid INTRODUCTION Bullous pemphigoid (BP) is a chronic autoimmune blistering disease characterized by pruritic, tense bullae and urticarial plaques. BP is associated with significant… Click to show full abstract
BMZ: basement membrane zone BP: bullous pemphigoid INTRODUCTION Bullous pemphigoid (BP) is a chronic autoimmune blistering disease characterized by pruritic, tense bullae and urticarial plaques. BP is associated with significant mortality, with 1-, 2-, and 5-year mortality rates of 19.46%, 29.13%, and 58.03%, respectively, in South Korea. The main pathogenesis involves IgG autoantibodies against hemidesmosomal proteins: BP 180 and BP 230. IgE autoantibodies are increasingly reported in BP. Herein we report a case of refractory BP with a fatal outcome and discuss the possible relationship between total serum IgE and disease activity.
Journal Title: JAAD Case Reports
Year Published: 2018
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