LAUSR

BSA: body surface area CRMO: chronic recurrent multifocal osteomyelitis HLA: human leukocyte antigen IBD: inflammatory bowel disease MRI: magnetic resonance imaging TNFi: tumor necrosis factor-a inhibitor INTRODUCTION Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory bone disease of unknown etiology. It most commonly affects children and can lead to persistent bone pain and bone destruction. Tumor necrosis factor-a inhibitors (TNFi) have been used to treat children with CRMO. However, TNFi may induce or worsen psoriasis in CRMO. Similar phenomena have been seen in inflammatory bowel disease (IBD), rheumatoid arthritis, and ankylosing spondylitis. Psoriasis induced by TNFi in children with CRMO has not beenwell documented beyond one case report. This case series aims to present 5 cases of patients with CRMO who had psoriasis after the initiation of TNFi.