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Wong-type dermatomyositis during anti–PD-1 therapy

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Checkpoint inhibitors used for cancer immunotherapy may also result in autoimmunity.1, 2 We present a case of Wong-type dermatomyositis complicating treatment with nivolumab, an inhibitor of the programmed cell death… Click to show full abstract

Checkpoint inhibitors used for cancer immunotherapy may also result in autoimmunity.1, 2 We present a case of Wong-type dermatomyositis complicating treatment with nivolumab, an inhibitor of the programmed cell death 1 (PD-1) receptor. Wong-type dermatomyositis is a rare variant of classic dermatomyositis with concurrent clinical and histopathologic findings mimicking pityriasis rubra pilaris.3 Our report of nivolumab-related Wong-type dermatomyositis expands the clinical spectrum of autoimmune diseases associated with checkpoint inhibitors.

Keywords: anti therapy; type dermatomyositis; dermatomyositis anti; dermatomyositis; wong type

Journal Title: JAAD Case Reports
Year Published: 2018

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