CLH: cutaneous lymphoid hyperplasia CTD: connective tissue diseases INTRODUCTION Morphea, also known as localized scleroderma, is characterized clinically by indurated skin and fibrosis of the dermis or subcutaneous tissue. Its… Click to show full abstract
CLH: cutaneous lymphoid hyperplasia CTD: connective tissue diseases INTRODUCTION Morphea, also known as localized scleroderma, is characterized clinically by indurated skin and fibrosis of the dermis or subcutaneous tissue. Its etiology is unknown. Based on clinical presentation, morphea is classified into plaque, generalized, bullous, linear, and deep morphea types. Several types of morphea may be present in the same patient. Cutaneous lymphoid hyperplasia (CLH) is defined as cutaneous B-cell infiltrates that resemble B-cell lymphoma clinically and histologically. Herein we report a case of CLH arising in pre-existing morphea plaques treated with methotrexate.
               
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