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Multifocal paraganglioma, mycosis fungoides, and monoclonal B-cell lymphocytosis in association with RAD51C mutation

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INTRODUCTION Mycosis fungoides is a rare, generally indolent non-Hodgkin T-cell lymphoma that typically presents with persistent, pruritic, scaly patches and plaques in sun-protected areas. Few genetic mutations have been consistently… Click to show full abstract

INTRODUCTION Mycosis fungoides is a rare, generally indolent non-Hodgkin T-cell lymphoma that typically presents with persistent, pruritic, scaly patches and plaques in sun-protected areas. Few genetic mutations have been consistently identified as being associated with mycosis fungoides. In this case report, we identify a patient with mycosis fungoides, multifocal paragangliomas, and a monoclonal B-cell lymphocytosis with a germline mutation in the RAD51C gene, a pathogenic mutation associated with breast, ovarian, pancreatic, and prostate cancers.

Keywords: mycosis; monoclonal cell; mycosis fungoides; cell lymphocytosis; mutation

Journal Title: JAAD Case Reports
Year Published: 2019

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