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A hydralazine-induced triumvirate: Lupus, cutaneous vasculitis, and cryptococcoid Sweet syndrome

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Hydralazine is a commonly prescribed antihypertensive medication that has been associated with both drug-induced lupus erythematosus and vasculitis.1 There is significant clinical, histopathologic, and serologic overlap between these entities. We… Click to show full abstract

Hydralazine is a commonly prescribed antihypertensive medication that has been associated with both drug-induced lupus erythematosus and vasculitis.1 There is significant clinical, histopathologic, and serologic overlap between these entities. We present an unusual case of hydralazine-induced autoimmune syndrome with elements of both drug-induced lupus and vasculitis, as well as Sweet syndrome–like cutaneous lesions with distinctive histopathologic cryptococcoid inflammatory cells.

Keywords: sweet syndrome; vasculitis; induced triumvirate; hydralazine; hydralazine induced; lupus

Journal Title: JAAD Case Reports
Year Published: 2019

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