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Two infants with blistering rashes originating on acral sites as a presenting sign of infantile bullous pemphigoid

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BP: bullous pemphigoid CBC: complete blood count WBC: white blood cell count INTRODUCTION Bullous pemphigoid (BP) is a rare autoimmune bullous disorder caused by IgG autoantibodies against hemidesmosomes at the… Click to show full abstract

BP: bullous pemphigoid CBC: complete blood count WBC: white blood cell count INTRODUCTION Bullous pemphigoid (BP) is a rare autoimmune bullous disorder caused by IgG autoantibodies against hemidesmosomes at the dermoepidermal junction. BP typically occurs in elderly patients but is rarely reported in infants and children. In infants, associations with infection and vaccinations have been proposed. Topical and systemic steroids are considered first-line treatment options. Disease severity and clinical course vary significantly between patients, and steroid-sparing medications may be necessary.

Keywords: blistering rashes; bullous pemphigoid; two infants; infants blistering; rashes originating; pemphigoid

Journal Title: JAAD Case Reports
Year Published: 2020

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