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Pigmented contact dermatitis in the axillae caused by hydroperoxides of limonene

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Fig 1. Pigmented contact dermatitis of the axillae caused by hydroperoxides of limonene. Patient’s older antiperspirant (Bottle 1, left) and newer anti-perspirant (Bottle 2, right). The older antiperspirant (left) was… Click to show full abstract

Fig 1. Pigmented contact dermatitis of the axillae caused by hydroperoxides of limonene. Patient’s older antiperspirant (Bottle 1, left) and newer anti-perspirant (Bottle 2, right). The older antiperspirant (left) was noticeably a darker shade of pink than the newer INTRODUCTION Limonene is a fragrance terpene that is derived from peel oil of citrus fruits. It is commonly used in household cleaning agents, cosmetics, personal care products, and fragrances for its fresh lemon aroma. Limonene on its own has low sensitization potential. However, upon exposure to air, limonene undergoes auto-oxidization to form different oxidation products, of which, hydroperoxides of limonene is a potent sensitizer and is known to cause allergic contact dermatitis. We report an unusual case of pigmented contact dermatitis caused by hydroperoxides of limonene.

Keywords: hydroperoxides limonene; caused hydroperoxides; contact dermatitis; pigmented contact

Journal Title: JAAD Case Reports
Year Published: 2020

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