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Primary cutaneous low-grade B-cell lymphoma treated with hydroxychloroquine

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CASE REPORT A 68-year-old man presented to his general practitioner with a violaceous nodule on the right aspect of the scalp. The patient had a medical history significant for hypertension,… Click to show full abstract

CASE REPORT A 68-year-old man presented to his general practitioner with a violaceous nodule on the right aspect of the scalp. The patient had a medical history significant for hypertension, dyslipidemia, and a herniated disc. Before presentation at our institution, a biopsy from the right side of the forehead was performed, but provided inconclusive results and a differential diagnosis that included lupus. The pathology report could not be successfully obtained from the patient’s records. Blood test results, conducted at that time, did not support a diagnosis of lupus. In accordance with the pathology report alone, for a presumed diagnosis of lupus, the patient began receiving hydroxychloroquine 200 mg twice daily for 2 months, and the lesion resolved and treatment was stopped. Several years later, he presented with several similar plaques on the scalp and was prescribed hydroxychloroquine by his family physician, with similar results. When he had a new lesion 12 years after the initial diagnosis, he was referred to the dermatology service. A repeated biopsy was performed from the scalp and was

Keywords: diagnosis; cutaneous low; pathology; primary cutaneous; grade cell; low grade

Journal Title: JAAD Case Reports
Year Published: 2020

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