LAUSR

MTHFR: methylenetetrahydrofolate reductase INTRODUCTION Scleromyxedema is a rare mucinosis characterized by a generalized, papular, sclerodermoid cutaneous eruption often accompanied by extracutaneous manifestation and associated with paraproteinemia. Sneddon syndrome is a progressive disease characterized by generalized livedo racemosa and recurrent cerebrovascular events with an autoimmune or thrombophilic base. To our knowledge, no cases of coexistence of these two disorders in the same patient have been reported. Herein we report the clinical, pathological, and laboratory findings of a patient with both scleromyxedema and Sneddon Syndrome.