APK: aquagenic palmoplantar keratoderma INTRODUCTION The pathogenesis of aquagenic palmoplantar keratoderma (APK) is not well understood. Typically, it occurs in those with cystic fibrosis, but idiopathic and drug-induced cases have… Click to show full abstract
APK: aquagenic palmoplantar keratoderma INTRODUCTION The pathogenesis of aquagenic palmoplantar keratoderma (APK) is not well understood. Typically, it occurs in those with cystic fibrosis, but idiopathic and drug-induced cases have been reported. Medications associated with APK include aspirin, nonsteroidal anti-inflammatory drugs, celecoxib, and clarithromycin. We describe the case of a young female with idiopathic APK who responded to therapeutic intervention with topical glycopyrronium.
               
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