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CK: creatine kinase INTRODUCTION Approximately 44% of patients on isotretinoin develop elevated levels of creatine kinase (CK), a proxy for potential muscle tissue damage. Mild elevations are typically transient and… Click to show full abstract
CK: creatine kinase INTRODUCTION Approximately 44% of patients on isotretinoin develop elevated levels of creatine kinase (CK), a proxy for potential muscle tissue damage. Mild elevations are typically transient and well-tolerated, whereas marked elevations can indicate rhabdomyolysis (CK level of $ 5 times the reference range [approximately 200 IU/L]) and can be life-threatening. Here, we present 2 physically active patients with clinically divergent presentations of elevated serum CK levels during isotretinoin therapy.
Journal Title: JAAD Case Reports
Year Published: 2022
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