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Disseminated cutaneous Mycobacterium chelonae infection as a presenting sign of ectopic adrenocorticotropic hormone syndrome

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ACTH: adrenocorticotropic hormone NTM: nontuberculosis mycobacterium INTRODUCTION Mycobacterium chelonae is a rapidly growing nontuberculosis mycobacterium (NTM). Infection with M chelonae typically results from cutaneous injury, injections, or other medical procedures.… Click to show full abstract

ACTH: adrenocorticotropic hormone NTM: nontuberculosis mycobacterium INTRODUCTION Mycobacterium chelonae is a rapidly growing nontuberculosis mycobacterium (NTM). Infection with M chelonae typically results from cutaneous injury, injections, or other medical procedures. Skin infections by the M chelonae complex are heterogeneous and can present as papules, pustules, ulcerating nodules, and deep lesions, such as furuncles and nodules with sinus tracts. Disseminated infections have been described in immunocompromised patients, including those receiving systemic steroids and immunosuppressants such as methotrexate and azathioprine. To our knowledge, a single case report previously described disseminated M chelonae in a patient with endogenous hypercortisolemia (Cushing syndrome). Here, we describe a case, in which endogenous hypercortisolemia secondary to ectopic adrenocorticotropic hormone (ACTH) syndrome resulted in disseminated M chelonae infection.

Keywords: infection; mycobacterium; mycobacterium chelonae; adrenocorticotropic hormone

Journal Title: JAAD Case Reports
Year Published: 2021

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