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An approach to a patient with suspected meat allergy due to underlying alpha-Gal syndrome in a resource-limited setting

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IgE: immunoglobulin E INTRODUCTION The alpha-Gal syndrome is a type of food allergy in which antibodies against the galactose a-1, 3-galactose are generated. Patients with alpha-Gal syndrome typically present with… Click to show full abstract

IgE: immunoglobulin E INTRODUCTION The alpha-Gal syndrome is a type of food allergy in which antibodies against the galactose a-1, 3-galactose are generated. Patients with alpha-Gal syndrome typically present with symptoms related to allergic reactions, such as pruritus, urticaria, angioedema, and even anaphylaxis 3 to 6 hours after eating meat. Diagnosis is often a combination of a compatible clinical presentation with additional testing that can include skin prick test, prick-by-prick testing, and serum immunoglobulin E (IgE) antibodies against galactose-a-1, 3-galactose. Management often includes dietary restriction of meat and meatderived products and appropriate treatment, when exacerbations occur. The goal of this report is to present an interesting case of alpha-Gal syndrome and describe some of the challenges associated with the management of this condition in a developing country.

Keywords: gal syndrome; alpha gal; meat; allergy; approach patient

Journal Title: JAAD Case Reports
Year Published: 2022

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