LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Biogenic synthesis of silver nanoparticles and evaluation of physical and antimicrobial properties of Ag/PVA/starch nanocomposites hydrogel membranes for wound dressing application

Photo by markuswinkler from unsplash

Abstract Silver nanoparticles (NPs) were synthesized using Diospyros lotus fruit extract. Plant biomolecules were extracted through two solvents i.e. water and methanol. Effect of both solvents on the extraction process… Click to show full abstract

Abstract Silver nanoparticles (NPs) were synthesized using Diospyros lotus fruit extract. Plant biomolecules were extracted through two solvents i.e. water and methanol. Effect of both solvents on the extraction process as well as effect of both extracts on the reduction of precursor salt to NPs has been studied and reported. Employing the synthesized Ag NPs as a component of nanocomposites, hydrogel membranes were prepared with starch and polyvinyl alcohol (PVA). Synthesized Ag NPs as well as prepared nanocomposites membranes were fully characterized through FTIR, XRD, SEM and UV–Visible spectroscopy. The ultimate tensile strength of the hydrogel membranes with 50 ppm Ag NPs was found to be highest among all the compositions while swelling tendency of the membranes was found to increase with increase in the NPs concentrations. Additionally, no significant decrease in gel fraction of the hydrogel membranes could be observed with the addition of NPs. However, addition of NPs resulted in reduced water evaporation from the membranes. Finally, anti-bacterial test of the Ag NPs as well as hydrogel membranes showed comparable results as shown for the ciprofloxacin, indicating the potential of such membranes to be used in wound dressing application.

Keywords: wound dressing; hydrogel membranes; dressing application; silver nanoparticles; nanocomposites hydrogel

Journal Title: Journal of Drug Delivery Science and Technology
Year Published: 2019

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.