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Abstract Doxorubicin-loaded mixed micelles (DOX-micelles) were formulated employing TPGS and a poloxamine (Tetronic® T1107) in order to investigate their pharmaceutical application as an alternative anticancer nanotherapy. DOX-micelles presented unimodal behaviour,… Click to show full abstract
Abstract Doxorubicin-loaded mixed micelles (DOX-micelles) were formulated employing TPGS and a poloxamine (Tetronic® T1107) in order to investigate their pharmaceutical application as an alternative anticancer nanotherapy. DOX-micelles presented unimodal behaviour, exhibiting average size values of 10.7 ± 0.2 nm and 10.4 ± 0.1 nm, before and after lyophilization, respectively. The in vitro cytotoxic effect of DOX-micelles was significantly higher (p
Keywords:
dox micelles;
doxorubicin;
loaded mixed;
effect;
doxorubicin loaded;
mixed micelles
Journal Title: Journal of Drug Delivery Science and Technology
Year Published: 2020
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Journal Title: Journal of Drug Delivery Science and Technology
Year Published: 2020
Link to full text (if available)
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recommendations!