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Mutations in SLURP1, encoding a secreted protein of keratinocytes, cause a palmoplantar keratoderma (PPK) known as mal de Meleda [1]. When the link between SLURP1 mutations and mal de Meleda… Click to show full abstract
Mutations in SLURP1, encoding a secreted protein of keratinocytes, cause a palmoplantar keratoderma (PPK) known as mal de Meleda [1]. When the link between SLURP1 mutations and mal de Meleda was uncovered, there was speculation that SLURP1 might be a ligand for a cell-surface receptor of keratinocytes [1]. Also, because the predicted structure of SLURP1 resembled cobra neurotoxins, there was speculation that SLURP1 might influence
Keywords:
keratoderma slurp1;
slurp1 slurp2;
slurp1;
palmoplantar keratoderma
Journal Title: Journal of dermatological science
Year Published: 2018
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Journal Title: Journal of dermatological science
Year Published: 2018
Link to full text (if available)
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recommendations!