LAUSR

Abstract The eco-friendly synthesis of Yb2O3 and IL-Yb2O3 NPs was performed by Andrographis Paniculata leaves extract. The XRD pattern described the crystalline behavior and the crystallite size was at 50 and 45 nm for Yb2O3 and IL-Yb2O3 NPs. The FTIR and Raman analyses illustrated the functional groups of Yb2O3 and IL-Yb2O3 NPs. The UV-visible analysis described the formation of synthesized NPs with the absorption peak at 227 and 239 nm. The photoluminescence study revealed the yellow color luminescent behavior of Yb2O3 and IL-Yb2O3 NPs. The formation of IL-Yb2O3 NPs with 25-75 nm particle size was revealed from DLS analysis. The SEM analysis explained the circular and rectangular morphology of Yb2O3 and IL-Yb2O3 NPs. The composition analysis of EDX showed the purity of Yb2O3 and IL-Yb2O3 NPs with the presence of only Yb and O peaks and also chemical elements of IL-Yb2O3 NPs was confirmed by XPS analysis. The HRTEM analysis explained the hexagonal structured formation of Yb2O3 and IL-Yb2O3 NPs. The antibacterial assay described the high inhibition of Yb2O3 and IL-Yb2O3 NPs on E.coli and S.aureus bacteria. The anti-diabetic assay revealed the biomedical behavior of Yb2O3 and IL-Yb2O3 NPs on α-Amylase. The anti-inflammatory assay found the potential denaturation of bovine serum albumin (BSA) by Yb2O3 and IL-Yb2O3 NPs. The antioxidant assay revealed the potential free radical scavenging behavior of Yb2O3 and IL-Yb2O3 NPs. The MTT assay found the biomedical potential action of Yb2O3 and IL-Yb2O3 NPs on the MCF-7 cancer cell line.