LAUSR

In this study, samples of daily foods, drinking waters, surface waters, and soils were collected and screened to investigate the external exposure of Sb and As from various intake pathways in typical Sb mining area. Biomarker samples of residents were analyzed to monitor internal exposure characteristic of Sb and As in human body. Exposure dosages of As and Sb and transfer of Sb and As from environment to human body were estimated based on the external and internal exposure. The following results were obtained: daily intakes of food accounted for major intakes of both Sb and As, and highlighted the significance of foods intakes from rice and vegetable. The results of Monte Carlo simulations showed that total daily intake of Sb(n = 1444)and As(n = 1131) approximately reached 1.08 × 10-2 mg/kg/d and 1.19 × 10-3 mg/kg/d, in which 98.82% and 63.07% of residents have exceeded the threshold dosages of Sb and As. The contaminants contents in biomarkers indicated that Sb exhibited the similar internal exposure as As, while the total transfer rate of Sb from environment to human were estimated as approximately 2.04-2.40 times lower than As. This study also suggested that drinking water is another important pathway with high bioavailability and male resident may present higher priority than female in uptake of Sb and As. The paper suggested the similarity and difference on bioavailability existed in Sb and its group V elements, As, that would provide the essential information on exposure of Sb and As in the typical Sb mine area.