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Abstract The effect of Korean red ginseng (KRG; Panax ginseng Meyer) against doxorubicin (DOX)-induced testicular inflammation was investigated. Male Sprague-Dawley rats were treated with DOX (1 mg mL−1 kg−1 week−1; intra-peritoneally) for 8 weeks, and… Click to show full abstract
Abstract The effect of Korean red ginseng (KRG; Panax ginseng Meyer) against doxorubicin (DOX)-induced testicular inflammation was investigated. Male Sprague-Dawley rats were treated with DOX (1 mg mL−1 kg−1 week−1; intra-peritoneally) for 8 weeks, and KRG water extract (EX1; 100 and EX2; 200 mg/kg/day; orally) was administered for 9 weeks starting one week before DOX exposure. The expression levels related to spermatogenesis, inflammatory and autophagy markers were evaluated using western blotting and reverse transcriptase polymerase chain reaction. DOX-induced a significant (p
Journal Title: Journal of Functional Foods
Year Published: 2018
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