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Holothuria leucospilota polysaccharides alleviate liver injury via AMPK and NF-κB signaling pathways in type 2 diabetic rats

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Abstract The study evaluated the beneficial effects of orally administered Holothuria leucospilota polysaccharides (HLP) on liver injury in diabetic rats. The results showed that HLP regulated liver glycogen, glycosylated serum… Click to show full abstract

Abstract The study evaluated the beneficial effects of orally administered Holothuria leucospilota polysaccharides (HLP) on liver injury in diabetic rats. The results showed that HLP regulated liver glycogen, glycosylated serum protein, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels. Simultaneously, HLP significantly reduced lipid accumulation in livers of diabetic rats (P

Keywords: holothuria leucospilota; polysaccharides alleviate; leucospilota polysaccharides; diabetic rats; liver injury

Journal Title: Journal of Functional Foods
Year Published: 2021

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