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Reaction of CF3-ynones with methyl thioglycolate. Regioselective synthesis of 3-CF3-thiophene derivatives

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Abstract Efficient regioselective synthesis of 3-CF3-substituted thiophene derivatives was elaborated using addition of methyl thioglycolate to CF3-ynones in the presence of sodium methoxide. Click to show full abstract

Abstract Efficient regioselective synthesis of 3-CF3-substituted thiophene derivatives was elaborated using addition of methyl thioglycolate to CF3-ynones in the presence of sodium methoxide.

Keywords: cf3 ynones; cf3; synthesis cf3; thiophene derivatives; regioselective synthesis; methyl thioglycolate

Journal Title: Journal of Fluorine Chemistry
Year Published: 2018

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