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Abstract The incorporation of a perfluoroalkyl group into heterocycles has received increasing attention. Herein we describe the synthesis of perfluoroalkylated indolizines via a tandem cyclization/aromatization process under mild conditions. In… Click to show full abstract
Abstract The incorporation of a perfluoroalkyl group into heterocycles has received increasing attention. Herein we describe the synthesis of perfluoroalkylated indolizines via a tandem cyclization/aromatization process under mild conditions. In contrast to previous synthetic methods, which are usually used to construct the pyrrole motif rather than the pyridine moiety in indolizines, our protocol relies on the formation of the pyridine rings.
Keywords:
tandem cyclization;
cyclization aromatization;
indolizines via;
via tandem;
perfluoroalkylated indolizines;
synthesis perfluoroalkylated
Journal Title: Journal of Fluorine Chemistry
Year Published: 2021
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Journal Title: Journal of Fluorine Chemistry
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!